ISB Innovations: Ultrasound-Based Tumor Biopsies
John Chevillet, PhD
I am trying to develop an ultrasound-based method to take a sample from a tumor, thus replacing needle biopsies. An ultrasound-based method would minimize complications, better diagnose cancers, and direct the use of targeted therapies for personalized medicine.
If I had $10,000, I could analyze the blood specimens we currently have for cancer dna to demonstrate what this method can tell us about the mutations driving a tumor. If I had $100,000, I could analyze a wide spectrum of molecules (DNA, RNA and protein) and start to define a biomarker signature panel that could be used as a foundation for a test more accurate than what we have now. If I had $1 million, I could partner with physicians and patients to test this method.
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