ISB News

New Baliga Lab Publication in Cell Systems

The Baliga Lab’s Dr. Christopher Plaisier was the lead author of the study “Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis” which published online in Cell Systems on July 14. Dr. Plaisier wrote a summary of the research:

3 Bullets:

  • Using data from TCGA and ENCODE, ISB researchers developed integrative database and analysis platforms that provide insight about the underpinnings of glioblastoma multiforme.
  • Researchers developed a way to intelligently discover combinations of small RNA molecules and drugs that can lead to synergistic effects.
  • They also Identified a never before seen association between increased levels of immune molecules, tumor immune cell infiltration, and decreased patient survival.

READ THE ARTICLE

A tweet from Dr. Nitin Baliga, the PI on the research paper.

Related Articles

  • Path-seq illustration

    Profiling Pathogen Gene Expression from Infected Host Cells

    Researchers at ISB reported a novel method, Path-seq, to profile expression of all MTB genes within infected mice. This study presents the most comprehensive transcriptome profiling of MTB from in vivo infection and a major technical advancement for studying any host-pathogen interaction.

    Read More
  • Biology students

    Biology Classes ‘Come Alive’ After Teacher’s Summer with ISB

    Kyle Kinzler, a high school biology teacher from Portland, Oregon, spent part of last summer at Institute for Systems Biology to evolve his curriculum and learn new ways to teach relevant, compelling and innovative content to his students. As a result, he says his classes has “come alive.”

    Read More
  • ISB's Dr. Sui Huang Earns Funding to Tackle Cancer's Biggest Questions

    ISB’s Professor Sui Huang, MD, PhD, has been announced by Cancer Research UK as a member of a global research team funded through its Grand Challenge competition — an international funding initiative that aims to answer some of the biggest questions facing cancer research.

    Read More
Show More Articles