ISB News

CRI, ISB, Sage Bionetworks Unveil Comprehensive Immunotherapy Tool

Three organizations on the forefront of cancer immunotherapy, systems biology and bioinformatics announced the release of the Cancer Research Institute iAtlas, a comprehensive web-based tool that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvironment.

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Dr. John Aitchison Taps Systems Biology, Collaboration to Attack Infectious Diseases

John Aitchison is a pioneer in the field of systems biology. He is a founding member of Institute for Systems Biology (ISB), he was the long-time director of the Center for Systems Biology, and now he serves as president and director of Center for Infectious Disease Research (CIDR).

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Dr. Jim Heath Takes Helm of ISB, Looks Toward the Future

Jim Heath took over as president of Institute for Systems Biology on January 1. To fully appreciate Heath’s relationship with ISB, you have to go back to its early days – shortly after the research organization was founded in 2000.

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Key Strategies for Implementing Proteomics-Based Tests Across Disease States Highlighted in Current Opinion in Biotechnology

ISB, Integrated Diagnostics and Sera Prognostics just announced a paper entitled, “The building blocks of successful translation of proteomics to the clinic,” by Leroy Hood and colleagues published online in Current Opinion in Biotechnology.

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Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s

Institute for Systems Biology (ISB) is among several organizations conducting a clinical trial testing how health coaching affects the cognitive function of patients with early-stage Alzheimer’s disease and analyzing longitudinal, multi-omic data to explore transitions in cognitive function over time.

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‘Fantastic Opportunity:’ ISB’s Scholars Program Offers Transformational Experience for Ambitious College Grads

ISB’s Systems Research Scholars Program (SRSP) is a two-year, fully funded training program for recent college graduates, and is designed to help transform exceptionally talented and ambitions post-baccalaureate students into the next generation’s pioneers of interdisciplinary research.

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High School Scientist Targets Sepsis, Earns $25,000 Scholarship Along the Way

Sriharshita Musunuri, 17, is looking to find and stop what causes sepsis, the top killer in American hospitals. She is collaborating with several ISB staff members, including mentor Chris Lausted, and just earned a $25,000 scholarship for her work.

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Lessons I Learned from My 17 Years as ISB President

Lee Hood co-founded Institute for Systems Biology in 2000, and has served as president of the institution since; on January 1, 2018, he left that role to serve as chief science officer of Providence St. Joseph Health. Here, Hood shares the many lessons he learned from 17 years at the helm of ISB.

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Dr. Sui Huang

New Principle for Eradicating Cancer: Leave No Dead Cells Behind

Dead cells, or cell debris, generated by treatments intended to eradicate tumor cells actually act as strong stimulators of tumor progression. The findings of ISB cancer biologist Sui Huang, his former mentee and longtime collaborator Dipak Panigrahy at Beth Isreal Deaconess Medical Center in Boston, and colleagues at Harvard Medical School were published in The Journal of Experimental Medicine.

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Bench to Blackboard: Q&A with Dr. Colleen Sheridan

Once an immunologist focusing on research at ISB, Colleen Sheridan followed her passion and became a tenure-track college biology professor focusing on teaching. Sheridan was awarded the Valerie Logan Leadership in Science Education Award, and describes her professional transformation in this Q&A.

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Igniting Curiosity, Catalyzing Change

At the 6th Annual Valerie Logan Luncheon held Thursday, the day’s theme – “Igniting Curiosity, Catalyzing Change” – was evident throughout. Every year, ISB celebrates Valerie Logan, the founder of our education programs, and all her work toward providing K-16 professional development for educators, high school STEM curriculum development, undergraduate research internships, and, crucially, student access to diverse mentors. This year’s event raised a record $140,000 to fund ISB’s education programs.

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ISB-CGC banner image

‘Pushing Cancer Research Forward:’ Powerful ISB Cancer Genomics Cloud Tool in Spotlight

Institute for Systems Biology, Google and CSRA have jointly created a cloud-based platform that allows researchers to quickly, reliably and securely access massive amounts of data in ways that, until now, haven’t been possible.

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Translational Research Fellows Program

ISB, Providence St. Joseph Health Launch Translational Research Fellows Program

ISB and Providence St. Joseph Health are leveraging their respective research and clinical expertise to attract exceptional individuals into the Translational Research Fellows Program, a three-year training program that offers early-stage scientists a chance to jumpstart their careers and provides mentorship from experts in systems biology and clinical research.

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Genome fingerprinting

Genome Comparison Easier with ‘Fingerprint’ Method

ISB researchers have developed a method of capturing a personal genome as a “fingerprint,” which will have a major impact on how quickly and efficiently genome sequences are compared.

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Postdoc Appreciation 2017

Postdoc Appreciation 2017

In honor of National Postdoc Appreciation Week in late September, ISB’s staff recently gathered to honor and celebrate all of our devoted and hardworking postdocs. The event included speeches from a number of faculty members. “Postdocs are the heart of ISB,” Dr. Nathan Price, professor and associate director, told the gathering.

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2017 ISB Intern Akanksha Bawa

2017 Undergrad Intern Showcase

Summer 2017 brought a fresh cohort of undergraduate students interested in exploring ISB’s research in the Summer Undergraduate Research Experience Program.

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Annual Report 2016

ISB Annual Report: Catalyzing A Revolution

ISB’s compass has always been oriented toward the future. Even when we reflect on the past year for each annual report, it’s always through the lens of what’s on the horizon. We are remarkably consistent in that regard, which is in no small part due to our president Dr. Lee Hood, whose vision is perpetually a decade – at least – ahead of everyone else.

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ISB Artwork Featured On Cover of Nature Biotechnology

Institute for Systems Biology and Arivale “Pioneer 100 Study” is featured on the cover of August’s Nature Biotechnology. The artwork was created by ISB’s Associate Director of Communications Allison Kudla in collaboration with contributing author John C. Earls, software engineer in Hood/Price Lab.

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