ISB News

Dr. Jim Heath Takes Helm of ISB, Looks Toward the Future

Jim Heath took over as president of Institute for Systems Biology on January 1. To fully appreciate Heath’s relationship with ISB, you have to go back to its early days – shortly after the research organization was founded in 2000.

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Lessons I Learned from My 17 Years as ISB President

Lee Hood co-founded Institute for Systems Biology in 2000, and has served as president of the institution since; on January 1, 2018, he left that role to serve as chief science officer of Providence St. Joseph Health. Here, Hood shares the many lessons he learned from 17 years at the helm of ISB.

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2017 ISB Intern Akanksha Bawa

2017 Undergrad Intern Showcase

Summer 2017 brought a fresh cohort of undergraduate students interested in exploring ISB’s research in the Summer Undergraduate Research Experience Program.

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Save the Date: Panel Discussion at Town Hall

Save the date! As part of ISB’s Annual Systems Biology Symposium, we will host a panel discussion at Town Hall on the evening of April 4. This year’s Symposium theme is “Emerging Technologies for Systems Biology.” The Panelists include: Atul Butte, MD, PhD, Director, Institute for Computational Health Sciences, and Professor of Pediatrics, University of California, San Francisco; Carol Dahl, PhD, Executive Director, The Lemelson Foundation; and Jacob Corn, PhD,…

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Pushing the Molecular Switches of Tuberculosis Into Overdrive to Map Interactions

3 Bullets: Mycobacterium tuberculosis (MTB) infects more than 1.5 billion people worldwide partly due to its ability to sense and adapt to the broad range of hostile environments that exist within hosts. To study how MTB controls its responses at a molecular level, ISB researchers and their collaborators at Seattle Biomed perturbed almost all MTB transcription factor regulators and identified the affected genes. This comprehensive map of molecular switches in…

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ISB 2014 Year in Review

ISB has had a busy year! Explore a year’s worth of headlines on this timeline.

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Cancer genomics visualization at ISB

It’s Easier to Go ‘Viral’ When Your Partner Happens to be Google

By ISBUSA Since we announced that we got a $6.5 million contract from NCI to develop the Cancer Genomics Cloud pilot project, we’ve gotten some great press from around the world. It doesn’t hurt that one of our partners is Google, of course. Here are some of the headlines from around the world: Puget Sound Business Journal: Cancer in the cloud: Institute for Systems Biology teams up with Google NBCNews.com:…

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ISB 2014 Retreat

ISB held its all-staff retreat in Leavenworth on Sept. 8 and 9. In order to do the kind of science we do, we need time away to connect with one another, recharge and envision big ideas. While there are plenty of sessions on our science, there are also plenty of opportunities to have a little fun. This year, we held an “open-mic” night. Several ISB staffers performed – including Dr….

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Lee Hood Receives IEEE Medal for Innovations in Healthcare Technology

Dr. Lee Hood received the IEEE Medal for Innovations in Healthcare Technology at a ceremony in Amsterdam on Aug. 23, 2014. Please watch a video of his acceptance speech here. IEEE Spectrum Magazine also published an article featuring an interview with Lee: “Medicine’s Next Big Mission: Understanding Wellness” Read article…

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Analyzing Family Genomics Reveals New Culprit in Rare Disease

3 Bullets: Adams-Oliver syndrome (AOS) is a rare congenital disease characterized by scalp lesions and limb defects. Additional vascular abnormalities and heart defects can lead to early death in some patients. By analyzing twelve families affected with the disease, we identified causal mutations in a new disease gene, NOTCH1, in five families. NOTCH1 is likely to be the major cause of AOS. NOTCH1 codes for a transcription factor that governs…

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NIH awards $10.9 million to National Center for Dynamic Interactome Research

New $10.9 Million Grant from NIH

The NIH's National Institute of General Medical Sciences has issued a Biotechnology Resource Grant of $10.9 million over five years to the National Center for Dynamic Interactome Research (ncdir.org) project. This project is a collaboration among The Rockefeller University, Institute for Systems Biology, Seattle BioMed, University of California at San Francisco, New York University and New York Structural Biology Center. Michael Rout, of The Rockefeller University, is the Program Director/Principal…

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Cover image for ISB's 2013 Annual Report.

ISB’s 2013 Annual Report is Now Available

Institute for Systems Biology has a dizzying breadth of research projects. But when we talk about what we do, it’s how we do it that matters most. The systems approach that we pioneered and exemplify continues to distinguish our ability to tackle the most complex biological and environmental challenges today. Because of how we apply our hallmark collaborative, cross-disciplinary and integrative approach, our collective success is greater than the sum…

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In the News: Lee Hood on the Future of Personalized Medicine

Dr. Lee Hood, president of ISB, was featured in a cover story for the spring 2014 issue of HFMA (Healthcare Financial Management Association) Leadership Magazine. He spoke on the future of personalized medicine. “Wellness is not going to emerge out of the current healthcare industry. New thrusts don’t emerge out of old bureaucracies. New approaches emerge out of new institutions that are set up for them.” – Dr. Lee Hood…

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100K Wellness Project article in Clinical Omics written by ISB's Lee Hood and Nathan Price.

100K Wellness Project Article by Lee Hood and Nathan Price in Clinical Omics

The latest press about the 100K Wellness Project is in the May 15 issue of Clinical Omics and features a piece by Dr. Lee Hood, president of Institute for Systems Biology (ISB), and Dr. Nathan Price, ISB’s associate director. Read “Promoting Wellness and Demystifying Disease: The 100K Project”

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It's National Cancer Research Month. Please visit aacr.org to learn more. Or please support Institute for Systems Biology directly at https://www.systemsbiology.org/support.

It’s National Cancer Research Month: How To Help

May has been designated "National Cancer Research Month" and we'd like to share a little about how ISB is using the systems biology approach to tackle some of the complexities of researching cancers. You can read our four-part series on how ISB's pioneering systems biology has made an impact and continues to clear new pathways for the cancer research field. Please visit aacr.org to learn more about NCRM. Support ISB's…

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Speakers Dr. Joe Gray, of Knight Cancer Institute of Oregon Health & Science University, and Dr. Carla Grandori, of Fred Hutchinson Cancer Research Center, answer questions during a panel discussion.

ISB Systems Biology Symposium Speaker Videos Now Available

ISB held its 13th Annual International Symposium: Systems Biology & Cancers on April 13-14. Please read more about our speakers and program. If you weren't able to attend or would like to refresh your memory of the talks, we have made a selection of the presentations available to view below. Or visit the playlist on ISB's YouTube channel.

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Lee Hood Wins IEEE Innovations in Healthcare Technology Award

Lee Hood Wins IEEE Medal for Innovations in Healthcare Technology

IEEE (Institute of Electrical and Electronics Engineers) announced that Dr. Lee Hood, president of Institute for Systems Biology, is the 2014 recipient of the Medal for Innovations in Healthcare Technology. He is being recognized for "pioneering contributions to DNA sequencing technologies that revolutionized life and health sciences." Read about all the medal recipients here.  

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ISB Baliga Lab Systems Science Workshop 2014

Free Systems Science Workshop for High School Teachers

FREE SUMMER SYSTEMS SCIENCE WORKSHOP AT ISB FOR TEACHERS: Registration for the summer systems science workshop for high school science, math and CTE teachers is now open. The workshop is hosted by Claudia Ludwig and Dina Kovarik, of the Baliga Lab at ISB, and takes place July 21-25. The focus is on how to implement systems science in the classroom. For more information about the workshop, please visit this site….

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